Table 2.
Cancer Site/Type | Before the First Diagnosis | After the First Diagnosis | All | ||||||
O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | |
Upper aerodigestive tract | 22 | 0.31 | 0.19–0.47 | 87 | 0.61 | 0.49–0.76 | 109 | 0.51 | 0.42–0.61 |
Salivary gland | 2 | 0.25 | 0.02–0.93 | 10 | 0.86 | 0.41–1.59 | 12 | 0.60 | 0.31–1.05 |
Esophagus | 2 | 0.08 | 0.01–0.30 | 47 | 0.88 | 0.65–1.18 | 49 | 0.63 | 0.47–0.83 |
Stomach | 13 | 0.10 | 0.05–0.18 | 171 | 0.96 | 0.82–1.12 | 184 | 0.59 | 0.51–0.69 |
Small intestine | 5 | 0.42 | 0.13–1.00 | 29 | 1.28 | 0.85–1.84 | 34 | 0.97 | 0.67–1.36 |
Colon | 65 | 0.38 | 0.29–0.48 | 361 | 1.00 | 0.90–1.11 | 426 | 0.78 | 0.71–0.86 |
Rectum | 33 | 0.35 | 0.24–0.49 | 167 | 0.82 | 0.70–0.95 | 200 | 0.66 | 0.57–0.76 |
Anus | 2 | 0.44 | 0.04–1.62 | 20 | 1.60 | 0.97–2.47 | 22 | 1.25 | 0.78–1.90 |
Liver | 6 | 0.08 | 0.03–0.17 | 182 | 1.21 a | 1.04–1.40 | 188 | 0.81 | 0.70–0.94 |
Pancreas | 4 | 0.05 | 0.01–0.14 | 139 | 1.00 | 0.84–1.18 | 143 | 0.67 | 0.56–0.79 |
Nose | 1 | 0.19 | 0.00–1.09 | 9 | 0.99 | 0.45–1.89 | 10 | 0.69 | 0.33–1.28 |
Lung | 16 | 0.09 | 0.05–0.14 | 435 | 1.01a | 0.92–1.11 | 451 | 0.75 | 0.68–0.82 |
Breast | 283 | 0.75 b | 0.66–0.84 | 1042 | 1.47 b | 1.38–1.56 | 1325 | 1.25 b | 1.18–1.31 |
Cervix | 49 | 0.57 b | 0.43–0.76 | 84 | 1.39 b | 1.11–1.72 | 133 | 0.85 | 0.71–1.01 |
Endometrium | 83 | 0.99 | 0.79–1.23 | 228 | 1.34 b | 1.17–1.53 | 311 | 1.35 b | 1.20–1.51 |
Ovary | 44 | 0.48 | 0.35–0.65 | 133 | 1.13 | 0.95–1.34 | 177 | 0.85 | 0.73–0.98 |
Other female genital | 7 | 0.56 | 0.22–1.16 | 27 | 1.18 | 0.78–1.72 | 34 | 0.94 | 0.65–1.31 |
Prostate | 39 | 0.19 | 0.13–0.26 | 373 | 0.54 | 0.49–0.60 | 412 | 0.45 | 0.41–0.50 |
Testis | 21 | 0.84 | 0.52–1.29 | 28 | 1.27 | 0.84–1.83 | 49 | 0.94 | 0.69–1.24 |
Other male genital | 4 | 0.81 | 0.21–2.09 | 12 | 1.24 | 0.64–2.17 | 16 | 1.06 | 0.60–1.72 |
Kidney | 19 | 0.23 | 0.14–0.37 | 158 | 1.09 | 0.93–1.27 | 177 | 0.78 | 0.67–0.91 |
Urinary bladder | 40 | 0.42 | 0.30–0.57 | 169 | 0.73 a | 0.63–0.85 | 209 | 0.63 | 0.55–0.72 |
Melanoma | 42 | 0.54 | 0.39–0.73 | 119 | 0.77 | 0.64–0.93 | 161 | 0.67 | 0.57–0.78 |
Skin squamous cell | 25 | 0.39 | 0.25–0.58 | 143 | 0.78 | 0.66–0.92 | 168 | 0.63 | 0.54–0.73 |
Nervous system | 46 | 0.44 | 0.32–0.58 | 158 | 1.06 | 0.90–1.24 | 204 | 0.80 | 0.69–0.92 |
Thyroid gland | 15 | 0.50 | 0.28–0.83 | 32 | 0.88 | 0.60–1.24 | 47 | 0.69 | 0.51–0.92 |
Endocrine glands | 43 | 0.89 | 0.65–1.21 | 92 | 1.08 | 0.87–1.32 | 135 | 1.01 | 0.84–1.19 |
Bone | 6 | 0.64 | 0.23–1.41 | 8 | 1.01 | 0.43–2.00 | 14 | 0.83 | 0.45–1.40 |
Connective tissue | 7 | 0.33 | 0.13–0.69 | 37 | 1.17 | 0.83–1.62 | 44 | 0.82 | 0.60–1.10 |
Non-Hodgkin lymphoma | 32 | 0.36 | 0.25–0.51 | 187 | 0.92 | 0.80–1.07 | 219 | 0.75 | 0.65–0.85 |
Hodgkin’s disease | 15 | 0.60 | 0.34–1.00 | 23 | 1.10 | 0.70–1.66 | 38 | 0.82 | 0.58–1.13 |
Myeloma | 12 | 0.38 | 0.20–0.67 | 58 | 0.87 | 0.66–1.12 | 70 | 0.71 | 0.55–0.89 |
Leukemia | 18 | 0.30 | 0.18–0.48 | 83 | 0.92 | 0.73–1.14 | 101 | 0.67 | 0.55–0.82 |
Cancer of unknown primary | 9 | 0.12 | 0.05–0.23 | 210 | 1.16 | 1.01–1.33 | 219 | 0.84 | 0.74–0.96 |
All | 1036 | 0.40 | 0.38–0.43 | 5101 | 1.00 | 0.97–1.03 | 6137 | 0.79 | 0.77–0.81 |
Note: O, observed number of cases; SIR, standardized incidence ratio; CI, confidence interval; Bold type, 95% CI does not include 1.00.
Smoking-adjusted SIRs for lung cancer and urinary bladder cancer 0.49 and 0.42, respectively. Alcohol-adjusted SIR for liver cancer 0.94.
Additionally adjusted for parity and age at first birth.