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. 2012 Mar 13;39(3):720–728. doi: 10.1093/schbul/sbs038

Fig. 2.

Fig. 2.

Ab-initio 3D modeling of SH2 domain (VAV3). (a) Wild type, note hydrogen bond between Glu741 and Lys735 (blue line); (b) Mutant type, hydrogen bond between Gly741 and Lys735 cannot be formed; (c) and (d) posphorylation potential of serine (blue), threonine (green), and tyrosine (red). Threshold is marked by horizontal gray line (phosphorylation analysis performed by NetPhos 2.0).