Table 3.
Brain Regions Whose Activity During Affect Rating of a Target (OTHER condition) Showed Greater Association With Target’s Expressivity in Healthy Controls Compared With Patients With Schizophreniaa
| Talairach Coordinates | ||||||
| Brain Region | H | x | y | z | t value | Cluster Size |
| Inferior parietal lobule (BA 40) | R | 37 | −51 | 36 | 5.31 | 3246 |
| Middle frontal gyrus (BA 9) | R | 35 | 40 | 27 | 5.21 | 296 |
| Inferior frontal gyrus (BA 46) | R | 47 | 43 | 13 | 4.90 | 157 |
| Anterior cingulate (BA 24) | R | 9 | 19 | 21 | 4.49 | 1641 |
| Superior frontal gyrus (BA 9) | L | −37 | 36 | 32 | 4.30 | 365 |
| Cingulate (BA 31) | R | 18 | −34 | 32 | 4.11 | 252 |
| Posterior cingulate (BA 30) | R | 18 | −54 | 16 | 4.09 | 175 |
| Middle occipital gyrus (BA 37) | L | −53 | −68 | 5 | 4.08 | 239 |
| Middle frontal gyrus (BA 9) | R | 49 | 17 | 32 | 3.75 | 369 |
| Lingual gyrus (BA 18) | L | −7 | −76 | −4 | 3.60 | 90 |
| Middle frontal gyrus (BA 6) | L | −40 | 7 | 53 | 3.53 | 80 |
| Inferior frontal gyrus (BA 45) | L | −35 | 29 | 9 | 3.52 | 321 |
| Fusiform gyrus (BA 19) | R | 25 | −75 | −12 | 3.41 | 74 |
| Lingual gyrus (BA 18) | L | −21 | −57 | 2 | 3.37 | 129 |
| Cuneus (BA 18) | L | −13 | −69 | 14 | 3.35 | 111 |
| Thalamus | R | 1 | −5 | 13 | 3.30 | 154 |
| Paracentral lobule (BA 6) | R | 1 | −30 | 61 | 2.97 | 69 |
Note: Abbreviations are explained in the first footnote to table 2.
The cluster size represents the number of voxels. Talairach coordinates represent the peak voxel of each cluster, where x, y, and z indicate the distance measured in millimeters from the anterior commissure in the sagittal, coronal, and horizontal planes, respectively. All clusters of activation reported in table 3 were significant at P < .01, uncorrected for multiple comparisons, with a minimum cluster size of 53 contiguous voxels, corresponding to a false-positive discovery rate of <5% across the whole brain as estimated by Monte Carlo simulation.