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(A) Concentration of endogenous and exogenous (bound + free) TGF-β1 in cartilage matrix after exposure to 10 ng/mL of exogenous active TGF-β1 or a TGF-β1-free solution (0 ng/mL) for up to 48 h. (B) Concentration of exogenous (bound + free) TGF-β1 in cartilage matrix after exposure to varying levels of exogenous active TGF-β1 (4–450 ng/mL) for 24 h.
