Table 2.

Experimentally determined binding parameters implemented in finite-element theoretical simulations

Case #	Nt/KD	Binding site density, Nt [ × 105 ng/mL]	Dissociation constant, KD [× 105 ng/mL]	Forward rate constant, kf [× 10−6 min.ng/mL−1]	Reverse rate constant, kr [min−1]	Partition coefficient, κ	TGF-β diffusivity, D [μm2/s]
1	636	4	0.0063	4.6	0.03	0.09	21.3
2	636	40	0.063	0.46	0.03	0.09	21.3
3	636	400	0.63	0.046	0.03	0.09	21.3