Table 3.
Adverse effect | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
Nausea/vomiting | 160 (61.1) | 48 (18.3) | - (-) | - (-) |
General fatigue | 28 (10.7) | 17 (6.5) | 1 (0.4) | - (-) |
Fever | 168 (64.1) | 27 (10.3) | - (-) | - (-) |
Abdominal pain | 121 (46.1) | 54 (20.6) | - (-) | - (-) |
Leucopenia | 13 (4.9) | 2 (0.7) | - (-) | - (-) |
Thrombocytopenia | 16 (6.1) | 2 (0.7) | - (-) | - (-) |
AST/ALT | 154 (58.8) | 46 (17.6) | - (-) | - (-) |
Liver abscess | - (-) | 2 (0.7) | 2 (0.7) | - (-) |
Hepatic/Renal failure | - (-) | - (-) | 1 (0.4) | - (-) |
Data are expressed as number of patients with percentages in parentheses. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.