Table 1. Parameters used in the simulations.

Parameter	Value	Unit	Description	References
a, h	10−5, 10−5	m	Cell radius and height	[12]–[13]
c	3•10−6	m	Nucleus radius	[12]–[13]
d, e	0, 5 •10−6	m	Nucleus location (r; z)	[12]–[13]
ε1, ε2	60, 120	Dimensionless	Relative dielectric permittivity of the cytoplasm and nucleoplasm	[37]
σ1, σ2	0.25, 0.5	S/m	Conductivity of the cytoplasm and nucleoplasm	[37]
V0	−0.033	V	Electric potential of the nucleus	[2], [17]
Jn	1500	A/m2	Current densities, top and bottom of the cylinder (cell model)	[6], [s5–s9]*
η	0.002	Pa•s	Viscosity of cytoplasm	[39], [s24,s28,s32]
ζ	−0.05	V	Zeta-potential of cellular membrane	[s15,s16]
DC, DN	14•10−12,0.04•10−12	m2/s	Diffusion coefficients of the messenger protein in the cytoplasm and nucleoplasm	[s46,s47], [s48]
wL, zL	2•10−6, 10−5	M	FRAP laser beam radii in radial and axial directions	[44]
KL	6	Dimensionless	Bleach efficiency	[44]

^*[s5], [s9], etc–means reference from the (“Methods S1. Parameters Justification” file).