Effects of adipose tissue depots on expression of inflammation-related genes in young and older adult rats. Values are expressed as means ± SE. WAT in the young group of rats is used as the reference tissue and set at 1. TNF-α, tumor necrosis factor-alpha; MCP-1, monocyte chemotactic protein-1; IL-6, interleukin 6; IL-10, interleukin 10; IL-18, interleukin 18; IL1-RA, interleukin 1 receptor antagonist; Adipo, adiponectin; WAT, epididymal white adipose tissue; BAT, subscapular brown adipose tissue; Abd PVAT, abdominal perivascular adipose tissue; Thor PVAT, thoracic perivascular adipose tissue; D, fat depot main effect; G, group main effect; DxG, fat depot by group interaction effect; Letter a denotes significantly different (P < 0.05) from WAT; letter b denotes significantly different (P < 0.05) from BAT; c denotes significantly different (P < 0.05) from Abd PVAT; and d denotes significantly different (P < 0.05) from Thor PVAT.