Fig. 1.

Time course of body weight changes during the exposure to chronic intermittent hypoxia (CIH) and sham treatments. CIH rats had a transient arrest of body weight gain on the first 2–3 days of exposure, after which they gained weight at a slower rate than the sham-treated group (4.3 vs. 5.2 g/day; see text for details). As a result, the mean body weight of the CIH group was significantly lower than for the sham-treated group throughout the exposure period (P = 0.007–0.05, unpaired t-tests).