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Differential signalling to JAK/STAT by IL-6 and LIF. Neonatal rat cardiomyocytes were treated with IL-6 (with or without sIL-6R) or LIF for the indicated times (min) in serum-free medium and harvested for Western Blot analysis. Blots were probed for: Panels A and B: Phospho-STAT 1 (Tyr701); Phospho-STAT3 (Tyr705)/Total STAT3; Panel C: Phospho-p38-MAPK (Thr180/Tyr182); Phospho-JNK (Thr183/Tyr185); Phospho-Erk1/2 (Thr202/Tyr204)/Total Erk2.
