Figure 3.

Effect of continuous PTH on blood-ionized calcium. Sixteen groups of mice from 8 different genotypes received a continuous infusion of PTH or vehicle for 8 days, as indicated (Npt-Wt: wild-type for both Npt2a and Npt2c and more as described in Figure 2). Blood-ionized calcium was measured prior to and 1, 2, 4, and 8 days after starting the infusion. Data were expressed as mean ± SEM. b, P < .05 (PTH vs vehicle of the same genotype, n = 6). *P < .05 [compared with Npt2-Wt basal levels (day 0), n = 12]; **P < .05 [compared with Npt2a^−/− basal levels (day 0), n = 12].