Facilitation of light responses in PLC hypomorph norpAP16 by rdgA1/+, ninaCP235, and rtp mutations. A–D: responses in norpAP16 hypomorph were enhanced on ninaCP235, rdgA1/+, and rtp backgrounds. Left: macroscopic responses elicited by flashes (arrow) containing ∼7.5 × 105 WT effective photons. Right: representative samples of quantum bumps in darkness after decay of the current to baseline. E and F: bar graphs summarizing the effect of rdgA/+, ninaCP235, and rtp backgrounds on bump amplitude (E) and peak response to flashes containing ∼7.5 × 105 WT effective photons (F) compared with single norpAP16 mutant controls (labeled +/+). (P16, n = 6–14; ≥50 bumps in each cell; double mutants, n = 5–19 cells).