Figure 8. Acute stress increases FGF2 expression in GFAP+ astrocytes in the dorsal hilus.
(A) There was no change in mean optical density of FGF2-ir in the DG following 3 hr immobilization or CORT injection. (B) Both immobilization and 40 mg/kg CORT injection significantly increased integrated optical density of FGF2-ir in GFAP+ cells in the hilus. One-way ANOVA, p=0.0024. *p=0.04 and 0.05, con v immob and 0 V 40 mg/kg CORT, respectively. (C) FGF2-ir integrated optical density in GFAP- cells of the hilus did not change. (D) Representative images of FGF2+ cells (green) that are GFAP+ (red; white arrows) or GFAP- in DG and hilus of a control and an immobilized rat. DAPI is blue. Scale bar = 10 μm.