TABLE II.

Serum IGF Axis Hormone Levels (Median Values; P-value From Kruskal–Wallis Test in LAPC-4 Study, Rank Sum Test for LNCaP Study)

Study group	IGF-1 (ng/ml)	IGFBP-1 (ng/ml)	IGFBP-2 (ng/ml)	IGFBP-3 (ng/ml)	IGF1/IGFBP3 ratio	Blood glucose (mg/dl)	Insulin (ng/ml)
LAPC-4 study
No RV (n = 10)	205	4.0	258	2,053	0.10	219	2.4
RV50 (n = 10)	162	3.2	319	1,928	0.08	206	1.1
RV100 (n = 9)	179	3.6	272	2,139	0.08	203	0.4
P-value	0.01	0.82	0.14	0.39	0.01	0.87	0.03
LNCaP study
No RV (n = 8)	128	9.3	206	1,747	0.07	216	6.0
RV50 (n = 9)	142	6.2	286	1,763	0.08	222	3.9
P-value	1.0	0.36	0.04	0.63	0.70	0.72	0.31
Combined
No RV (n = 18)	179	5.8	208	2,035	0.09	217	4.6
RV50 (n = 19)	148	4.9	307	1,884	0.08	215	2.3
P-value	0.05	0.46	0.01	0.10	0.14	0.91	0.13