Figure 4.

Production of IL-1β, IL-10 and IL-17 in the lungs of mice infected with K. rhinoscleromatis, Kp52.145 or Kp110.

A. BALB/c mice were injected with saline or infected with 2.10⁷ K. rhinoscleromatis or 2.10⁴ Kp52.145 for 1, 3 or 5 days. Lungs were homogenized and cytokines were measured in the extracts by ELISA. Data are mean ± SEM from 8 to 15 mice from two independent experiments.

B. Mice were injected with saline or infected with 2.10⁷ K. rhinoscleromatis, Kp52.145 or Kp110 strains. Cytokines were measured at different days post infection (1, 2, 3 and 5 for K. rhinoscleromatis; 1, 3 and 5 for Kp110; 1 and 2 for Kp52.145). Data are mean ± SEM from 3 to 9 mice from two independent experiments.