Table 2.

This table is a summary of the effects of treatment on transsulfuration metabolites.

Laboratory test	Treatment group	Pre-treatment*	Post-treatment*	% change	p-value**
Trans-dermal glutathione (n)
Plasma cysteine (μmol/L)	12	19.4±11.2	24.7±12.9	21	<0.05
Plasma taurine (μmol/L)	13	51.4±21	68.1±32.2	25	<0.05
Plasma reduced glutathione (μmol/L)	13	3.06±0.57	3.43±0.4	11	NS
Plasma oxidized gluathione (μmol/L)	13	0.47±0.17	0.45±0.16	−4	NS
Plasma sulfate (μmol/g P)	13	950±186	1,095±231	13	<0.01
Plasma free sulfate (μmol/g P)	13	1.23±0.37	1.47±0.45	16	NS
Whole-blood glutathione (μmol/L)	11	977±275	1.075±336	9	NS
Oral glutathione (n)
Plasma cysteine (μmol/L)	13	17.6±8.5	24±10.6	27	<0.05
Plasma taurine (μmol/L)	13	45.8±12.7	56.6±13.6	19	<0.05
Plasma reduced glutathione (μmol/L)	13	3.22±0.54	3.83±0.63	16	<0.05
Plasma oxidized glutathione (μmol/L)	13	0.53±0.15	0.57±0.13	7	NS
Plasma sulfate (μmol/g P)	13	863±291	1,087±188	21	<0.01
Plasma free sulfate (μmol/g P)	13	1.41±0.52	1.6±0.5	12	NS
Whole-blood glutathione (μmol/L)	13	984±371	1,106±317	12	NS

^*Mean ± Standard Deviation;

^**Wilcoxon Matched-Pairs Signed-Ranks Test Statistic.

NS – Not Statistically Significant.