Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Apr 17;3:91. doi: 10.3389/fonc.2013.00091

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Le, Maranon, Altina, Battaglia and Bailey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

PMC Copyright notice

TERRA co-localization at telomeres. (A) 2D analysis of TERRA and TRF2 foci. Merging of the green (TERRA) and red (TRF2/telomeres) channels denotes potentially co-localized foci as yellow signals. (B) 3D analysis of TERRA and TRF2 foci. Deconvolution and 3D reconstruction of 22 stacks per cell nuclei provided a high-resolution perspective of TERRA co-localization at individual telomeres. Navigation of the 3D image provided a defined representation of telomere location throughout the cell nucleus, as well as TERRA distribution; i.e., either bound (co-localized with telomere) or free (not co-localized with telomere). Scale bar = 8 microns.