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. 2013 Apr 17;3:91. doi: 10.3389/fonc.2013.00091

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Copyright © 2013 Le, Maranon, Altina, Battaglia and Bailey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Total number of TERRA foci (bound and free). Experimental groups consisted of: control (DMSO) and DNA-PK inhibitor (NU7026); control (mock) and hnRNP A1 depleted (siRNA). (A) In MCF-10A, statistically significant increases in the total number of TERRA foci were observed for both NU7026 and siRNA treatments (*p < 0.05). (B) Statistically significant increases in the total number of TERRA foci were also observed in MCF-7 for both treatments (*p < 0.05). Data are ± SEM for n = 40 TERRA positive cells.