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. 2013 Apr 17;3:91. doi: 10.3389/fonc.2013.00091

Figure 8.

Figure 8

Frequencies of TRF2, TERRA, and co-localized foci in MCF-10A and MCF-7. 3D reconstruction and analysis of co-localization facilitated distinction between bound TERRA (TERRA foci co-localized at telomeres = dark blue bar), and free TERRA (difference between total TERRA foci = gray bar and co-localized/bound TERRA = dark blue bar). Number of telomere foci are normalized to 1.00 (light blue bar). Overall relationships are maintained, but the balance of free to bound TERRA is influenced by hTR, DNA-PKcs, and hnRNP A1 interactions.