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. Author manuscript; available in PMC: 2014 Apr 5.
Published in final edited form as: Mol Biosyst. 2013 Apr 5;9(4):586–595. doi: 10.1039/c2mb25429h

Figure 2. GPCR localizations and trafficking pathways in interphase cells.

Figure 2

Two different GPCRs (blue and red) are shown in this cartoon to illustrate the different membrane trafficking pathways that they can go through. The blue GPCR goes through the lysosomal degradation pathway and the red GPCR goes through the recycling pathway. The two pathways can coexist for a given GPCR. Cells’ responses to GPCRs can happen through external ligand-induced signaling cascades, as well as through internalized GPCRs.