. 2013 Apr 16;104(8):1720–1730. doi: 10.1016/j.bpj.2013.02.051

Table 2.

ITC-derived thermodynamic parameters for the binding of FGF1 to FGFR2c in the absence and presence of heparin hexa- and octasaccharide

Titration	K_D^a (nM)	ΔG (kcal mol⁻¹)	ΔH^b (kcal mol⁻¹)	−TΔS (kcal mol⁻¹)	n^c
FGF1-FGFR2c	4310	−7.2	−6.9	−0.3	1.0
[FGF1:6-mer]-FGFR2c	325	−9.9	−5.6	−3.3	0.9
[FGF1:8-mer]-FGFR2c	826	−8.0	−26.2	18.2	2.4

Errors in K_D are <14.0%.

Errors in ΔH are <4.5%.

Errors in experimentally derived values of n are <3.5%.