Table 2.
Titration | KDa (nM) | ΔG (kcal mol−1) | ΔHb (kcal mol−1) | −TΔS (kcal mol−1) | nc |
---|---|---|---|---|---|
FGF1-FGFR2c | 4310 | −7.2 | −6.9 | −0.3 | 1.0 |
[FGF1:6-mer]-FGFR2c | 325 | −9.9 | −5.6 | −3.3 | 0.9 |
[FGF1:8-mer]-FGFR2c | 826 | −8.0 | −26.2 | 18.2 | 2.4 |
Errors in KD are <14.0%.
Errors in ΔH are <4.5%.
Errors in experimentally derived values of n are <3.5%.