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. 2013 Apr 16;8(4):e62196. doi: 10.1371/journal.pone.0062196

Table 2. ARV EC50 values for inhibition of HIV-1 in different cell types.

EC50 (µM) +/− SEa (µM)
ARV SVG PFA PBMC MDM
Abacavir 0.056±0.011 0.004±0.001 0.117±0.028 0.010±0.003
Lamivudine 1.448±0.204 0.317±0.055 0.315±0.107 0.036±0.059
Stavudine 0.578±0.189 5.963±0.622 0.179±0.061 0.042±0.046
Zidovudine 0.017±0.003 1.311±0.130 0.008±0.002 0.005±0.002
Efavirenz 0.002±0.000 0.002±0.000 0.001±0.000 0.001±0.000
Etravirine 0.001±0.000 0.001±0.000 0.001±0.000 0.001±0.000
Nevirapine 0.045±0.006 0.114±0.020 0.182±0.068 0.166±0.253
Raltegravir 0.004±0.001 0.007±0.001 0.003±0.001 0.016±0.010
a

Mean 50% effective concentration±the standard error from n = 4 independent assays.

SVG, fetal astrocyte cell line; PFA, primary fetal astrocytes; PBMC, peripheral blood mononuclear cells; MDM, monocyte-derived macrophages.