Table 5. GO terms in Molecular Function overrepresentated in the enriched TF genes.

Subset	GO Term	p-value*	Transcripts
9 Promoter-enriched TFs
	Cell Differentiation	6.02E-04	PPARG (×2.68), RXRA (×1.57), NFATC4 (×0.63), EGR1 (×2.18), GATA2 (×3.59), MYCN (×2.35), NKX2-5 (1.21)
	ER-nucleus signaling pathway	9.22E-03	SREBF1 (×1.75), NFE2L2 (×2.97)
596 differentially expressed genes
	Cell Differentiation	7.87E-16	ACTA1, ADA, ADAM17, ADM, ALS2, ALX1, ANGPTL4, ANKRD1, ANPEP, ARHGAP24, AVPR1A, BMP6, BNIP3, BPGM, C1S, CAPN2, CHRD, CITED2, CLIC4, COL4A1, CRYAB, CTHRC1, CXCL5, DLX5, EDN1, EGR1 *, EIF2B1, EIF2B3, F11R, F2R, FGF2, FHL1, FST, FSTL3, FYN, GATA2, GATA6, GJA1, GREM1, HOXB7, ID1, IL15, IRF1, ITGA1, ITGB1, JAK2, KLF4, LAMA5, LGALS3, LOC360228, LRRK2, MDK, MGP, MGST1, MYCN, MYH10, MYH11, NAB1, NBL1, NBN, NDRG2, NES, NFATC4, NKX2-5, PDGFRA, PDLIM5, PDLIM7, PGF, PHGDH, PICALM, PLA2G2A, PLCG2, PPARG, PRPF19, PSAP, RARRES2, RND1, RXRA, SELENBP1, SFRP2, SHC1, SLC1A3, SMAD4, SMARCD3, STAR, STAT5B, TACC1, TCF21, TCF4, TGFB1, TGFB2, THBS4, TMEM204, TNMD, TRPV4, TWIST2, UNC5B, VAMP5, VEGFA, VEGFC, WT1, ZFP36L1

Functional classification is shown for 104 gene transcripts represented as differentially expressed between ASCs of LEW and PVG. The average changes (fold change) validated by quantitative RT-PCR are given in parentheses.

^*Bolded genes in the 596 gene set represent those were found in the motif-enriched TF genes.