Table 1. Variants detected by whole genome re-sequencing of an affected Border Collie.
Filtering step | Number of variants |
Variants in the whole genomea | 2,519,661 |
Variants in the critical 3.53 Mb interval on CFA 2 | 3,173 |
Variants in the critical interval that were absent from 12 other dog genomes | 243 |
Non-synonymous variants in the whole genomea | 68,303 |
Non-synonymous variants in the critical 3.53 Mb interval on CFA 2 | 17 |
Non-synonymous variants in the critical interval that were absent from 12 other dog genomes | 3 |
The sequences were compared to the reference genome (CanFam 3) from a Boxer. Only variants that were homozygous in the affected Border Collie are reported.