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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Cell Mol Neurobiol. 2013 Mar 17;33(4):551–558. doi: 10.1007/s10571-013-9925-8

Fig. 1.

Fig. 1

Effect of AGS3 expression on acute regulation of AC isoforms. a. Acute inhibition of A23187 (10 μM)-stimulated cAMP accumulation was measured following incubation with quinpirole as indicated in HEK293 cells stably expressing AC1 and the D2LDR, or AC1 and the D2LDR together with AGS3-Venus. b. Cyclic AMP accumulation was quantified in HEK293 cells stably expressing AC2 and the D2LDR with or without AGS3-Venus following acute treatment with PMA (1 μM) and increasing concentrations of quinpirole as indicated. Data points represent mean ± S.E.M. of at least three independent experiments performed in duplicate