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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Anesthesiology. 2012 Nov;117(5):1006–1017. doi: 10.1097/ALN.0b013e3182700ab9

Fig. 2.

Fig. 2

Delayed emergence in Dbh−/− mice is not due to a relative volatile anesthetic overdose. (A) Time to LORR in Dbh−/− and Dbh+/− mice when each group is exposed to their respective ED95 dose for eliciting LORR. (B) Time until RORR in Dbh−/− (black) and Dbh+/− (colored) mice following a 2 hour exposure to each group’s respective volatile anesthetic ED95 (n=12/group). There is a significant effect of genotype on emergence F1,66=12.33, p < 0.0003, but not upon induction F1,66=0.14, p=0.7132. Bars show mean ± SEM; LORR: loss of righting reflex; RORR: return of righting reflex; Sevo: sevoflurane; Iso: isoflurane; Halo: halothane; Dbh: dopamine β-hydroxylase.