Table 3. Inhibition of TcPRAC proline racemization measured by polarimetry.
Inhibitor | Inhibitor concentration | Racemization Inhibition |
(–) | (–) | 0.0% |
PYC | 10.0 µM | 56.9% |
OxoPA | 3.0 µM | 50.0% |
Br-OxoPA | 10.0 µM | 81.3% |
Br-OxoPA | 2.5 µM | 50.0% |
Inhibitor | Inhibitor concentration | Racemization Inhibition |
(–) | (–) | 0.0% |
PYC | 10.0 µM | 56.9% |
OxoPA | 3.0 µM | 50.0% |
Br-OxoPA | 10.0 µM | 81.3% |
Br-OxoPA | 2.5 µM | 50.0% |