Table 4. New inhibitors induce a decrease of cellular uptake of T. cruzi.
Inhibitor concentration (µM) | |||||||
Compound | 0 | 3 | 10 | 30 | 100 | 1000 | |
Endocytic index (EI) | PYC | 45 | nd | 44 | nd | 30 | 25 |
OxoPA | 57 | 42 | 23 | 21 | nd | nd | |
Br-OxoPA | 57 | 78 | 42 | 29 | nd | nd |