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. 2013 Apr 16;8(4):e61838. doi: 10.1371/journal.pone.0061838

Table 1. Microarray analysis of human blastocysts in patients undergoing in vitro fertilization and preimplantation genetic screening.

Observations Advanced maternal age Recurrent miscarriage Total
No. of cycles 51 21 72
Average age 40.2±2.8 33.2±2.2
No. of zygote (2 pronuclei) 375 197 572
No. (%)* of blastocysts biopsied 246 (65.6) 137 (69.5) 383 (67.0)
No. (%) of samples with DNA signals 242 (98.4) 135 (98.5) 377 (98.4)
No. (%) of normal embryos 87 (36.0)a 71 (52.6)b 158 (41.9)
No. (%) of abnormal embryos** 155 (64.0)a 64 (47.4)b 219 (58.1)
No. (%) of patients with embryo(s) for transfer 33 (64.7)c 19 (90.5)d 52 (72.2)
*

Blastocyst rate, out of zygotes (2 pronuclei).

**

Abnormal embryos include aneuploidy, chromosome deletions and duplications.

ab

P<0.01 within the same row.

cd

P<0.05.