. 2013 Apr 16;8(4):e61395. doi: 10.1371/journal.pone.0061395

Table 2. Comparison of models where protection from infection and time to onset of parasitemia depend on (i) anti-CSP antibodies and CSP-specific CD4⁺ T cells; (ii) anti-CSP antibodies only; (iii) CSP-specific CD4⁺ T cells only; and (iv) vaccination status only.

	Parameter estimates
Model	n	σ_n	µ	σ_µ	VE _s	β_ab	α_ab	β_CMI	ΔAIC
antibodies & CD4+ T cells	150	194	2136	4460	–	6.62	1.32	1367	0
antibodies only	156	210	2056	4205	–	5.83	1.38	–	4.34
vaccine status only	74	96	4463	9340	0.97	–	–	–	29.30
CD4⁺ T cells only	202	447	658	1444	–	–	–	489	76.62

Parameters are as defined in Table 1 and VE_s is the probability that a sporozoite is killed for the vaccination status only model. The ranking of models by AIC highlights the finding that the data are best explained by a model that includes both anti-CSP antibody titres and numbers of CD4⁺ T cells, and that a model with anti-CSP antibody titres only fits better than one with CD4⁺ T cells only.

Table 2. Comparison of models where protection from infection and time to onset of parasitemia depend on (i) anti-CSP antibodies and CSP-specific CD4+ T cells; (ii) anti-CSP antibodies only; (iii) CSP-specific CD4+ T cells only; and (iv) vaccination status only.

Table 2. Comparison of models where protection from infection and time to onset of parasitemia depend on (i) anti-CSP antibodies and CSP-specific CD4⁺ T cells; (ii) anti-CSP antibodies only; (iii) CSP-specific CD4⁺ T cells only; and (iv) vaccination status only.