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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Neurobiol Dis. 2013 Mar 5;54:94–104. doi: 10.1016/j.nbd.2013.02.015

Fig 8.

Fig 8

The SST2R agonist octreotide prevented SE induced by continuous hippocampal stimulation (CHS). (A, B, C), Representative EEG traces from the cortex (Cx) and hippocampus (Hc) at the end of CHS (A) and 1 hr (B) and 5 hr (C) after the end of CHS in animals treated with i.c.v.-administered saline or octreotide (50 μg) 1.5 hr before electrical stimulation. (D), The time course of octreotide control of electrographic seizure is displayed. The onset and persistence of seizure freedom in octreotide-pretreated animals was studied by analyzing seizure freedom at various time points up to 5 hr following SE.