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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Neurobiol Dis. 2013 Jan 8;54:216–224. doi: 10.1016/j.nbd.2012.12.014

Fig. 7. Interleukin (IL)-1β deficient mice had better histological and neurological function outcome than wild-type mice after middle cerebral arterial occlusion (MCAO).

Fig. 7

The results were evaluated at 24 h after the MCAO. A: Brain slices stained with 2,3,5-triphenyltetrazolium chloride from representative mice. B: Percentage of infarct volume in ipsilateral hemisphere volume. Results are the means ± S.E.M. (n = 6 – 8). C: Neurological deficit scores evaluated immediately before the animals were euthanized for the assessment of infarct sizes (data are presented in panel B) or assigned 7 to the animals that died before the end time point for observation. Results are presented in a box plot format (n = 6 – 8). ●: lowest or highest score (the score will not show up if it falls in the 95% interval); between lines: 95% interval of the data; inside boxes: 25–75% interval including the median of the data. D: The performance on rotarod. Mice were tested before and 24 h after the MCAO and the speed-latency index ratio of these two tests are presented. Results are the means ± S.E.M. (n = 6 – 8). * P < 0.05 compared with the wild-type mice.