Table 1.
Physiological data of rats during transient middle cerebral arterial occlusion (MCAO).
| MCAO group | MCAO + isoflurane group | |||||
|---|---|---|---|---|---|---|
| Before MCAO | During MCAO | after MCAO | Before MCAO | During MCAO | After MCAO | |
| MABP (mmHg) | 102 ± 8 | 105 ± 7 | 104 ± 7 | 101 ± 6 | 103 ± 6 | 103 ± 6 |
| Heart rate (beat/min) | 387 ± 15 | 391 ± 17 | 393 ± 18 | 393 ± 15 | 389 ± 16 | 395 ± 16 |
| Temperature (°C) | 37.0 ± 0.2 | 37.0 ± 0.1 | 36.9 ± 0.1 | 37.0 ± 0.1 | 37.0 ± 0.2 | |
| EtCO2 (mmHg) | 35 ± 4 | 36 ± 4 | 35 ± 4 | 36 ± 4 | 34 ± 5 | |
| SpO2 (%) | 97 ± 1 | 96 ± 1 | 97 ± 1 | 97 ± 1 | 96 ± 1 | 97 ± 1 |
Arterial samples were taken 10 min before and after the onset of MCAO as well as 20 min after MCAO. There were no temperature and EtCO2 data after MCAO for the MCAO group because those rats were awake. Data are means ± S.D. (n = 17 – 18). There were no statistical differences in these physiological data among the rats post-treated with or without 2% isoflurane for 60 min at the onset of reperfusion. MABP: mean arterial blood pressure. EtCO2: end-tidal CO2; SpO2: pulse oximeter oxygen saturation.