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. 2013 Apr 16;8(4):e61641. doi: 10.1371/journal.pone.0061641

Figure 4. P188 protectes HT22 hippocampal cells against OGD/R-induced cytotoxicity.

Figure 4

(A) Cell viability with different concentrations of p188 following OGD 18 h/R 24 h injury or under normal condition (−3, −4, −5 and −6 denoted 10−3 M, 10−4 M, 10−5 M and 10−6 M, respectively, ##, P<0.01 and ###, P<0.001 vs. without P188 in control groups, **, P<0.01; ***, P<0.001 vs. without P188 in OGD/R condition). (B) LDH leakage induced by OGD18 h/R 24 h injury or in normal condition with different concentrations of p188. #, P<0.05; ##, P<0.01 vs. without P188 in control groups. *, P<0.05; ***, P<0.001 vs. without P188 in OGD/R condition). (C) Representative microphotographs of propidium iodide (PI) fluorescence merged with white bright-light. HT22 cells were under normal condition without P188 or treated with OGD 18 h/R 24 h with or without P188.