CD11b is upregulated in both the hippocampus and entorhinal cortex at T0 as shown in representative photomicrographs for (A, E) controls (T0: n=7; T28: n=7; black bars) and rats exposed to binge (C, F) ethanol (T0: n=8; T28: n=8; grey bars). Higher magnification of microglia seen in the hippocampus are shown for both (H) control and (I) ethanol. Quantifications of OX-42 immunoreactivity for the subregions of the hippocampus were significantly different and are shown: (B) CA1, (D), CA2/3, and (G) DG as well as the (J) entorhinal cortex. Scale bar in B=500µm; H=300µm; J=10µm. *p<0.05