Table 1. Clinical characteristics of patients with viral hepatitis-associated HCC who underwent liver transplantation.

Characteristic	HBV-associated HCC (N = 7,162)	HCV-associated HCC (N = 496)	P-value
Gender (male/female)	6,518/642*	406/90	<0.001
Age (years), no. (%)			<0.001
18–30	130 (1.82)	2 (0.40)
30–40	959 (13.39)	8 (1.61)
40–50	2,563 (35.79)	72 (14.52)
50–65	3,180 (44.40)	326 (65.73)
≥65	330 (4.61)	88 (17.74)
Number of tumors#, median (interquartile range)	1 (1,3)	2 (1–4)	<0.001
Diameter of largest tumor<$>\raster(70%)="rg1"<$>, median (interquartile range), cm	4 (2.5–7)	3.3 (2.5,5.0)	<0.001
Sum of tumor diameters▴, median (interquartile range), cm	5 (3,10)	5 (3,9.5)	0.631
Preoperative AFP level★, median (interquartile range), ng/ml	142.66 (14.45,1,000)	55.78 (11.95,590.15)	<0.001
Downstaging, no. (%)	2,541 (35.48)	247 (49.80)	<0.001
TACE	1,680 (23.46)	146 (29.44)
RFA	271 (3.78)	46 (9.27)
Systemic chemotherapy	109 (1.52)	6 (1.21)
Percutaneous ethanol injection	40 (0.56)	9 (1.81)
Combination treatment	441 (6.16)	40 (8.06)
Vascular invasion, no. (%)	2,087 (29.14)	137 (27.62)	0.471
Venous invasion	1,555 (21.71)	101 (20.36)
Portal vein intrahepatic branch	934 (13.04)	67 (13.51)
Portal vein right or left branch	853 (11.91)	35 (7.06)
Main portal vein	844 (11.78)	47 (9.48)
Hepatic vein	240 (3.35)	14 (2.82)
Inferior vena cava	76 (1.06)	7 (1.41)

^*Gender was not specified in two cases;

^#1145 cases reported with missing nodules data and 144 cases with abnormal nodules were deleted;

^{<$>\raster(70%)="rg1"<$>}790 cases reported with missing size data and 301 cases with abnormal size were deleted;

^▴2352 cases reported with missing data and 286 cases with abnormal data were deleted;

^★746 cases reported with missing AFP and 179 cases with abnormal AFP were deleted.

Abbreviations: HCC, hepatocellular carcinoma; AFP, alpha fetoprotein; TACE, transcatheter arterial chemoembolization; RFA, Radiofrequency ablation.