Table 3. Cox proportional hazards model.
Overall survival | Tumor free survival | Hepatitis free survival | |||||||||||||
N = 4732<$>\raster(70%)="rg1"<$> | N = 4732<$>\raster(70%)="rg1"<$> | N = 4732<$>\raster(70%)="rg1"<$> | |||||||||||||
Factor★ | Group | Reference group | P | Hazard ratio | 95% Confidence interval | P | Hazard ratio | 95% Confidence interval | P | Hazard ratio | 95% Confidence interval | ||||
Hepatitis | HBV | V.S. | HCV | <.001 | 0.516 | 0.42 | 0.63 | <.001 | 0.636 | 0.53 | 0.76 | <.001 | 0.545 | 0.45 | 0.66 |
Preoperative AFP | 0–125 | V.S. | ≥500 | <.001 | 0.718 | 0.64 | 0.81 | <.001 | 0.698 | 0.63 | 0.77 | <.001 | 0.722 | 0.65 | 0.81 |
125–200 | 0.296 | 0.882 | 0.70 | 1.12 | 0.002 | 0.719 | 0.58 | 0.89 | 0.168 | 0.848 | 0.67 | 1.07 | |||
200–500 | 0.134 | 0.883 | 0.75 | 1.04 | 0.093 | 0.887 | 0.77 | 1.02 | 0.087 | 0.870 | 0.74 | 1.02 | |||
Size of largest tumor | ≤5 cm | V.S. | >5 cm | <.001 | 0.696 | 0.62 | 0.78 | <.001 | 0.665 | 0.60 | 0.73 | <.001 | 0.711 | 0.64 | 0.80 |
Number of tumor nodules | ≤4 | V.S. | >4 | <.001 | 0.756 | 0.67 | 0.86 | <.001 | 0.766 | 0.68 | 0.86 | <.001 | 0.781 | 0.69 | 0.89 |
TNM staging | Stage I | V.S. | Stage IV | <.001 | 0.469 | 0.37 | 0.57 | <.001 | 0.469 | 0.37 | 0.57 | <.001 | 0.489 | 0.39 | 0.61 |
Stage II | <.001 | 0.532 | 0.43 | 0.63 | <.001 | 0.532 | 0.43 | 0.63 | <.001 | 0.537 | 0.45 | 0.65 | |||
Stage III | 0.017 | 0.820 | 0.70 | 0.97 | 0.046 | 0.865 | 0.75 | 1.00 | 0.029 | 0.834 | 0.71 | 0.98 | |||
Vascular invasion | Yse | V.S. | No | <.001 | 1.538 | 1.37 | 1.73 | <.001 | 1.470 | 1.33 | 1.63 | <.001 | 1.510 | 1.34 | 1.70 |
Preoperative MELD score | 6–20 | V.S. | 31–40 | <.001 | 0.512 | 0.40 | 0.66 | <.001 | 0.591 | 0.47 | 0.75 | <.001 | 0.543 | 0.42 | 0.70 |
21–30 | 0.005 | 0.659 | 0.49 | 0.88 | 0.008 | 0.694 | 0.53 | 0.91 | 0.009 | 0.683 | 0.51 | 0.91 |
<$>\scale 48%\raster="rg1"<$>Cases in which data for any of the variables listed was missing (N = 2926) were excluded.
Adjusted for transplant year, recipient gender, recipient age and graft type (cadaveric/living).