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(A) Image of the unfixed liver revealed hepatomegaly without gross metastasis. (B) Microscopic examination of the liver revealed diffuse infiltration by pleomorphic cells with some glandular formation. (C) Immunohistochemical staining for E-cadherin expression in the metastatic nodule in the lung was strongly positive, (D) that of metastatic tumor cells in the liver was negative (arrow).
