Table III.
Cox regression analysis of prognostic parameters for recurrence-free survival in bladder cancer (Backward: LR).
| Variable | B | SE | Wald | df | P-value | Exp (B) | 95% CI for Exp (B)
|
|
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | |||||||
| cIAP1-N+Survivin-N | 0.617 | 0.256 | 5.827 | 1 | 0.016 | 0.539 | 0.327 | 0.89 |
| Stage (MI vs. NMI) | 0.959 | 0.364 | 6.962 | 1 | 0.008 | 0.383 | 0.188 | 0.781 |
| Grade (high vs. low) | 0.752 | 0.353 | 4.55 | 1 | 0.033 | 0.471 | 0.236 | 0.941 |
| cIAP1-C+ cIAP2+XIAP | 0.585 | 0.267 | 4.792 | 1 | 0.029 | 0.557 | 0.33 | 0.941 |
| Stage (MI vs. NMI) | 0.937 | 0.376 | 6.195 | 1 | 0.013 | 0.392 | 0.187 | 0.82 |
| Grade (high vs. low) | 0.653 | 0.355 | 3.374 | 1 | 0.066 | 0.521 | 0.259 | 1.045 |
| Survivin-C+Livin | 0.575 | 0.268 | 4.59 | 1 | 0.032 | 0.563 | 0.332 | 0.952 |
| Stage (MI vs. NMI) | 0.942 | 0.378 | 6.221 | 1 | 0.013 | 0.39 | 0.186 | 0.817 |
| Grade (high vs. low) | 0.6 | 0.354 | 2.863 | 1 | 0.091 | 0.549 | 0.274 | 1.1 |
cIAP1-N, nuclear cIAP1; Survivin-N, nuclear Survivin; cIAP1-C, cytoplasmic cIAP1; Survivin-C, cytoplasmic Survivin; NMI, non-muscle invasive; MI, muscle invasive. LowcIAP1-N+Survivin-N=scoring 0 and +1–2; LowcIAP1-C+cIAP2+XIAP=scoring 0 and +1–3;LowSurvivin-C+Livin=scoring 0 and +1–2; HighcIAP1-N+ Survivin-N=scoring +3–4 and +5–6; HighcIAP1-C+cIAP2+XIAP=scoring +4–6 and +7–9; HighSurvivin-C+Livin=scoring+3–4 and +5–6. B, coefficient; SE, standard error; df, degrees of freedom. Significantly different values are indicated in bold.