Table 3. Genotypes and allele frequencies of tested samples in this study.
genotype | N (n = 186) | Frequency (%) | Expected genotype frequency under HWE(%) | HapMap frequency HCB (%) | Allelea | Allele frequency (%) | HW (p-value)b | |
rs4784227 | CC | 93 | 50.00 | 51.52 | 66.7 | C | 71.77 | 0.31 |
CT | 81 | 43.55 | 40.52 | 24.4 | T | 28.23 | ||
TT | 12 | 6.45 | 7.97 | 8.9 | ||||
rs1219648 | AA | 66 | 35.48 | 34.66 | 40 | A | 58.87 | 0.64 |
AG | 87 | 46.77 | 48.43 | 46.7 | G | 41.13 | ||
GG | 33 | 17.74 | 16.92 | 13.3 | ||||
rs3803662 | CC | 13 | 6.99 | 8.59 | 6.7 | C | 29.30 | 0.29 |
CT | 83 | 44.62 | 41.43 | 44.4 | T | 70.70 | ||
TT | 90 | 48.39 | 49.98 | 48.9 | ||||
rs889312 | CC | 41 | 22.04 | 22.64 | 27.3 | C | 47.58 | 0.74 |
AC | 95 | 51.08 | 49.88 | 45.5 | A | 52.42 | ||
AA | 50 | 26.88 | 27.48 | 27.3 | ||||
rs750749 | TT | 143 | 76.88 | 77.74 | 80 | T | 88.17 | 0.26 |
CT | 42 | 22.58 | 20.86 | 17.8 | C | 11.83 | ||
CC | 1 | 0.54 | 1.40 | 2.2 | ||||
rs749292 | GG | 62 | 33.33 | 30.07 | 8.9 | G | 54.84 | 0.07 |
GA | 80 | 43.01 | 49.53 | 55.6 | A | 45.16 | ||
AA | 44 | 23.66 | 20.40 | 35.6 |
increased risk allele in bold
p value was calculated using chi test