Figure 7. Role of estrogen receptor in E₂-mediated suppression of HIV-infection.

A) Expression of ERα (black bars) and ERβ (grey bars) detected by real time RT-PCR in CD4⁺ T-cells (N = 3) and macrophages (N = 4). Bars represent mean ± SEM from 3 and 4 different donors for CD4⁺ T-cells and macrophages respectively. ND: non-detected. B) Released p24 detected by ELISA in the culture media of CD4⁺ T-cells and macrophages after 7 days of infection. Bars represent mean ± SEM from 4 replicates. Representative of 3 independent experiments. Rx: Raloxifene. *P<0.05.