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. 2013 Apr 17;8(4):e61506. doi: 10.1371/journal.pone.0061506

Figure 2. Role of Thy-1 in HUVEC migration.

Figure 2

(a) Treatment of HUVEC with IL-1β (10 nM) for 24 h significantly increased the level of Thy-1 protein and decreased the migrated cell number. Values represent the means±s.e.mean. (n = 4). *p<0.05 different from control group. # p<0.05 different from the IL-1β-treated group. (b) Treatment of HUVEC with PMA (20 ng/mL) for 24 h caused a 3.83-fold increase of the Thy-1 protein level (upper panel) and a 54% reduction of the migrated cell number (bottom panel). Values represent the means±s.e.mean. (n = 4). *p<0.05 different from control group. # p<0.05 different from the PMA-treated group. (c) Transfection with Thy-1 siRNA increased the HUVEC migration. Values represent the means±s.e.mean. (n = 3). *p<0.05. Co, control.