Table 1. FTL_0304, FTL_0291, FTL_0325 and FTL_0057 mutants are highly attenuated for virulence in BALB/c and C57BL/6 mice.
| Strains | 1×106 CFUa | 1×107 CFUa | ||
| BALB/c | C57BL/6 | BALB/c | C57BL/6 | |
| F. tularensis LVS | 0/5 | 0/5 | 0/5 | 0/5 |
| FTL_0304 | 5/5 | 5/5 | 5/5 | 5/5 |
| FTL_0291 | 5/5 | 5/5 | 5/5 | 5/5 |
| FTL_0325 | 5/5 | 5/5 | 5/5 | 5/5 |
| FTL_0057 | 5/5 | 5/5 | 5/5 | 5/5 |
a
6–8 weeks old mice were infected i.n. with either F. tularensis LVS or the indicated mutants and monitored for mortality for 28 days. Data are shown as number of mice survived/total number of mice infected.