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. 2013 Apr 17;8(4):e60732. doi: 10.1371/journal.pone.0060732

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© 2013 Poletti et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Top row. Yearly incidence of HZ (average in dark green, 95% CI in light green),of natural HZ – i.e., by HZ cases occurring among unvaccinated individuals that have experienced natural varicella – (average in red,95% CI in orange) and of HZ caused by the vaccine strain (average in blue, 95% CI in light blue) per 1,000 individuals as obtained by adopting the parallel fit approach and by simulating the two-dose scenario, which assumes the administration of a first dose to 1 year-old individuals (90% coverage) and a second dose to 5 years-old individuals (80% coverage), in Finland (a) in Italy (b) and in the UK (c). Results are based on 1,000 model realizations.