Table II.

Marker variation.

Time	VEGF (pg/ml)	T-Regs (n/ml)	Estradiol (ng/ml)	PGR (ng/ml)	FSH (mU/ml)	LH (mU/ml)
Baseline (100 patients)	421±75	115±20	95.9±6	1.61±03	14.9±1.7	8.4±1
1 year	134±29	84±14	8.34±1.2	0.4±0.2	3.14±0.3	0.37±0.2
(100 patients)	P<0.0001	P<0.0001	P<0.0001	P<0.0001	P<0.0001	P<0.0001
2 years	88±12	54±21	5.3±0.8	0.32±1.1	2.65±0.4	0.32±0.2
(100 patients)	P<0.0001	P<0.0001	P<0.0001	P<0.0001	P<0.0001	P<0.0001
4 years	55±21	35±18	5.7±0.7	0.44±1.1	2.14±0.4	0.25±0.2
(100 patients)	P<0.0001	P<0.0001	P<0.0001	P<0.0001	P<0.0001	P<0.0001

Values are presented as mean ± SD. VEGF, vascular endothelial growth factor; T-Regs, T-regulatory cells; FSH, follicle-stimulating hormone; LH, luteneizing hormone; PGR, progesterone. P-values vs. baseline value.