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Effect of CR on extinction learning and retention in mice lacking SERT. Neither (a) Day 1 extinction learning (n=11, 12) or (b) extinction retention over 2 days (n=11, 12) are improved in female SERT −/− mice. Wild-type (SERT +/+) littermates showed improvements on both measures ((a) n=8, 9; (b) n=8, 9). Differences analyzed by ANOVA. All results are presented as means±SEM. **p⩽0.01.
