Figure 5.

Effects of fluoxetine and CR on extinction learning and retention. (a) Fluoxetine does not significantly improve extinction learning on day one of extinction training in either AL (n=17, 8) or CR (n=17, 7) mice. (b) Fluoxetine improves extinction retention in female AL mice (n=17, 8), but does not significantly increase extinction retention in CR mice (n=17, 7). Statistical significance analyzed using ANOVA with Fisher's least significant difference procedure. All results are presented as means±SEM. *p<0.05.