Figure 3. Fewer lymphocytes infiltrate the CNS in CD146^EC-KO mice than in WT mice following the induction of passive EAE.

Flow cytometry analysis of CD45^highCD11b⁻ lymphocytes (a), CD4⁺ T_H1 and T_H17 lymphocytes (b) and CD146⁺ T cells (c) from the CNS of CD146^EC-KO and WT mice with passive EAE. The data represent three independent experiments; 5 mice/group. *, p < 0.05, **, p < 0.01.