Table 3. Multivariate analyses of disease outcome according to BMI.
|
All |
Tamoxifen |
Tamoxifen+aminogluthtetimide |
|||
---|---|---|---|---|---|---|
DFS | HR | 95% CI | HR | 95% CI | HR | 95% CI |
Overweight+obese vs normal weight | 1.25 | 0.95–1.64 | 1.27 | 0.86–1.87 | 1.23 | 0.83–1.82 |
Overweight vs normal weight | 1.15 | 0.85–1.55 | 1.35 | 0.89–2.04 | 0.99 | 0.64–1.53 |
Obese vs normal weight |
1.45 |
1.03–2.02 |
1.15 |
0.70–1.87 |
1.78 |
1.12–2.83 |
Distant recurrence-free survival | ||||||
Overweight+obese vs normal weight | 1.62 | 1.09–2.42 | 1.48 | 0.85–2.58 | 1.81 | 1.02–3.22 |
Overweight vs normal weight | 1.54 | 1.00–2.35 | 1.58 | 0.88–2.86 | 1.51 | 0.81–2.83 |
Obese vs normal weight |
1.79 |
1.11–2.87 |
1.31 |
0.66–2.60 |
2.43 |
1.25–4.70 |
Overall survival | ||||||
Overweight+obese vs normal weight | 1.49 | 0.99–2.23 | 1.29 | 0.74–2.24 | 1.73 | 0.96–3.13 |
Overweight vs normal weight | 1.34 | 0.87–2.07 | 1.22 | 0.66–2.24 | 1.48 | 0.78–2.80 |
Obese vs normal weight | 1.81 | 1.12–2.91 | 1.41 | 0.71–2.77 | 2.28 | 1.16–4.51 |
Abbreviation: BMI=body mass index; CI=confidence interval; DFS=disease-free survival; HR=hazard ratio.